![]() ![]() On August 23, 2021, FDA announced the first approval of a COVID-19 vaccine. CDC head Dr.Comirnaty Information Pfizer-BioNTech Fact Sheets Pfizer-BioNTech Fact Sheet Translations Información sobre las vacunas para el COVID-19.Where to find the new omicron-specific Covid boosters, from Walgreens and CVS to local pharmacies and clinics.Sign up now: Get smarter about your money and career with our weekly newsletter "We should keep our eyes wide open to what side effects and adverse events might occur, and still keep in mind that this is a new product," Offit says. You can still be confident going in, he says - just don't be 100% sure what to expect. The BA.1 trials only tested a few hundred people, which is a relatively small sample size compared to the thousands of Americans set to receive the new BA.5 doses, Offit notes. Its updated booster has 25 micrograms targeting the original strain, and 25 targeting the omicron subvariants. Moderna's monovalent shot contains 50 micrograms of mRNA per dose targeting the original strain. The updated booster shots c ontain the same number of micrograms, with 15 targeting the original strain and the other 15 targeting BA.4 and BA.5. The new shots have the same dosage amounts as the original vaccines, which further suggests that their safety profiles could be similar, Offit says.Ī single dose of Pfizer's monovalent vaccine contains 30 micrograms of mRNA targeting the original Covid strain. The same concept held true during the last round of booster shots. You're only eligible for the new boosters if you've completed a primary vaccination series, meaning most people will have already received at least two doses ahead of time. ![]() Severe side effects are "generally" most common after receiving a second dose of a vaccine, not after receiving a third or fourth dose, says Offit. Moderna's trial found that nearly 59% of participants experienced fatigue, but only about 4% experienced that at a Grade 3 level, which is defined as significant fatigue that prevents daily activity. Roughly 26% of participants experienced a mild or moderate headache, while only 0.3% experienced a severe one. Pfizer's trial found that about 52% of participants that received the BA.1 shot experienced mild pain at the injection site, 8% experienced moderate pain and only 0.3% experienced severe pain. But notably, in those clinical trials, the severity of the side effects was very mild. That's a familiar list: It's the same group of side effects that came with the original formulations.
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